Termination of Mn(III)-based oxidative cyclizations by trapping with azide.

نویسندگان

  • Barry B Snider
  • Jeremy R Duvall
چکیده

The radicals formed in Mn(III)-based oxidative free-radical cyclizations of beta-keto esters and malonate esters can be trapped with sodium azide and Mn(III) to give cyclic and bicyclic azides in 30-80% yield. Reduction of the azide gives bi- and tricyclic lactams. [reaction: see text]

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عنوان ژورنال:
  • Organic letters

دوره 6 8  شماره 

صفحات  -

تاریخ انتشار 2004